Product ID:HIPPURAN I 131 INJECTION
MSDS Date:01/01/1995
FSC:6505
NIIN:00F035477
MSDS Number: BYHZS

MALLINCKRODT MEDICAL INC

2703 WAGNER PLACE
MARYLAND HEIGHTS, MO 63043-3421
US

Emergency Phone: 314-770-7800

Info Phone: 314-770-7800/314-895-2000

Cage: FO650

MALLINCKRODT MEDICAL INC

MARYLAND HEIGHTS, MO 63043-3421 US

Telephone: 314-770-7800/314-895-2000

Cage: FO650

HIPPURAN I 131

CAS: 881-17-4

Fraction By Weight: <1%

DISODIUM EDETATE; ACETIC ACID, (ETHYLENEDINITRILO)TETRA-,

CAS: 139-33-3

RTECS: AH4375000

Fraction By Weight: 0.005%

SODIUM CITRATE, TRISODIUM SALT, CITRIC ACID

CAS: 68-04-2

RTECS: GE8300000

Fraction By Weight: 0.02%

BENZOIC ACID, 4-HYDROXY-, PROPYL ESTER, PROPYLPARABEN

CAS: 94-13-3

RTECS: DH2800000

Fraction By Weight: 0.03%

METHYL PARAHYDROXYBENZOATE, METHYLPARABEN

CAS: 99-76-3

RTECS: DH2450000

Fraction By Weight: 0.1-1%

1,2-PROPANEDIOL (PROPYLENE GLYCOL)

CAS: 57-55-6

RTECS: TY2000000

Fraction By Weight: 37.5%

Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:RADIOACTIVE MATERIAL. SKIN:
IRRITATION. EYES: MECHANICAL IRRITATION. INGESTION: ASYMPTOMATIC
PHYSIOLOGICAL UPTAKE BY THYROID GLAND/OTHER TISSUES. UPTAKE OF
I-131 BY THYROID GLAND CAN RESULT IN SLIGHT TO TOTAL THYROID
DYSFUNCTION. CHRONIC RADIATION EXPOSURE MAY CAUSE CANCER, LEUKEMIA,
GENETIC & TERATOGENIC EFFECTS.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION.

First Aid:NOTIFY RADIATION SAFETY PERSONNEL IMMEDIATELY. INHALATION:
ASSESS/DOCUMENT AMOUNT OF MATERIAL. INGESTION: ASSESS/DOCUMENT
AMOUNT OF I-131 IN THYROID GLAND. THYROID BLOCKING AGENT MAY BE
WARRANTED. SKI N: WASH AFFECTED AREA THOROUGHLY W/SOAP& WATER.
ALWAYS BLOT DRY. DON'T ABRADE SKIN. EYES: FLUSH W/WATER FOR 15
MINS/UNTIL NO MORE RADIOACTIVITY CAN BE REMOVED. OBTAIN MEDICAL
ATTENTION IN ALL CASES.

Flash Point:NON-FLAMMABLE
Extinguishing Media:USE MEDIA APPROPRIATE FOR SURROUNDING FIRE.
Fire Fighting Procedures:WEAR A NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS W/FULL FACEPIECE OPERATED IN PRESSURE DEMAND/OTHER
POSITIVE PRESSURE MODE & FULL PROTECTIVE CLOTHING.

Spill Release Procedures:IF PRODUCT IS RECEIVED IN A LEAKING
CONDITION/ANY LOSS/RELEASE OF RADIOACTIVE CONTENTS OCCURS, NOTIFY
YOUR RADIATION SAFETY DEPARTMENT & MALLINCKRODT @ 314-770-7800.
(SEE SUPP)

Handling and Storage Precautions:STORE BETWEEN 59-86F. KEEP HANDLING
TIME TO MINIMUM & USE APPROPRIATE SHIELDING. USE SYRINGE SHIELDS &
TONGS WHEN HANDLING.
Other Precautions:STORAGE & DISPOSAL OF PRODUCT SHOULD BE CONTROLLED
IAW/APPROPRIATE REGULATIONS OF FEDERAL/STATE GOVERNMENT AGENCY
AUTHORIZED TO LICENSE USE OF THIS RADIONUCLIDE. DON'T SMOKE,
EAT/DRINK WHERE RADIOACTI VE MATERIALS ARE HANDLED/STORED.

Respiratory Protection:NOT EXPECTED TO REQUIRE USE OF PERSONAL
RESPIRATOR.
Ventilation:PROPERLY SEALED CONTAINERS AREN'T EXPECTED TO REQUIRE ANY
SPECIAL VENTILATION.
Protective Gloves:DISPOSABLE PLASTIC, LATEX, RUBBER
Eye Protection:SAFETY GLASSES.
Other Protective Equipment:DISPOSABLE LABCOAT
Supplemental Safety and Health
SPILL PROCEDURES: ALL CLEANUP OPERATIONS SHOULD BE PERFORMED
IAW/STANDARD OPERATING PROCEDURES, NRC/OTHER APPLICABLE FEDERAL,
STATE & LOCAL REGULATIONS. WASTE DISPOSAL: WASTE HIPPURAN I 131 IS
NON-HAZ ARDOUS IF NOT RADIOACTIVE/A BIOHAZARD. RADIOACTIVE MATERIAL
UN 2982.

Boiling Pt:B.P. Text:212F
Melt/Freeze Pt:M.P/F.P Text:32F
Solubility in Water:COMPLETE
Appearance and Odor:CLEAR, COLORLESS LIQUID IN A 10 ML GLASS VIAL W/NO
ODOR.

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:HEATED TO DECOMPOSITION: RADIOACTIVE
FUMES CONTAINING I-131.

Waste Disposal Methods:HIPPURAN I 131 IS RADIOACTIVE WASTE UNTIL
ACTIVITY HAS DECAYED TO NONDETECTABLE LEVELS. RADIOACTIVE WASTE
MUST BE HANDLED IAW/NRC, FEDERAL, STATE & LOCAL REGULATIONS.
MEDICAL WASTE, BLOOD, BLOOD PRODU CTS/SHARPS MUST BE HANDLED AS
BIOHAZARD. (SUPP)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.